Micro Needle Therapy — also known as dermapen microneedling or collagen induction therapy — is one of the most versatile and effective skin treatments available today. Using a specialized device containing multiple ultra-fine needles, it creates thousands of controlled micro-punctures in the skin’s surface, triggering the body’s natural wound-healing response and stimulating deep collagen and elastin production.
At Akarshan Skin & Hair Clinic in Kathmandu, microneedling is offered across a full range of protocols — from standalone dermapen to PRP, meso solution, tranexamic acid, exosome, PDRN, and MNRF — so every patient receives the exact combination their skin needs.
What Is Micro Needle Therapy?
Micro Needle Therapy uses a dermapen — a medical-grade device containing multiple fine needles arranged in a tip — to create precise, controlled micro-injuries in the skin at an adjustable depth. This controlled injury activates the skin’s cascade of healing:
- Platelets and growth factors rush to the micro-injury sites
- Fibroblasts (collagen-producing cells) are activated
- New collagen and elastin fibers are synthesized
- Skin cell turnover accelerates
- The surface gradually reveals smoother, firmer, and more even-toned skin
The micro-channels created also serve as direct delivery pathways for topical serums — PRP, meso solutions, hyaluronic acid, growth factors — allowing them to penetrate far deeper than surface application alone, dramatically enhancing their efficacy.
Microneedling Protocols at Akarshan
1. Dermapen Microneedling Alone
Standard microneedling using the dermapen device to create controlled micro-injuries and stimulate collagen induction. Suitable for skin rejuvenation, mild acne scars, fine lines, and texture improvement. Minimal downtime of 1–2 days. NRS 4,000 per session.
2. Microneedling + PRP (Vampire Facial)
The patient’s own blood is drawn and centrifuged to extract Platelet-Rich Plasma. The PRP is applied immediately after microneedling, penetrating deeply through the micro-channels to deliver concentrated growth factors directly to the regenerating tissue. This combination dramatically enhances collagen stimulation, accelerates healing, and improves results for acne scars, aging skin, and overall rejuvenation. Starting from NRS 5,000 per session.
3. Microneedling + Meso Solution
A pharmaceutical meso solution — a targeted blend of hyaluronic acid, vitamins, peptides, and growth factors — is applied after microneedling for patients who prefer or require an alternative to blood-derived treatment. Particularly effective for hydration, brightening, and pigmentation concerns. NRS 6,000 per session.
4. Microneedling + Tranexamic Acid — NRS 6,000
Tranexamic acid is a powerful skin-brightening and depigmenting agent that inhibits melanin synthesis. When delivered through microneedling micro-channels, it penetrates far deeper than topical application, making it significantly more effective for treating melasma, stubborn hyperpigmentation, post-acne dark marks, and uneven skin tone. This protocol is particularly recommended for patients whose primary concern is pigmentation or dullness. NRS 6,000 per session.
5. Microneedling + Exosome — NRS 10,000
Exosomes are nano-sized vesicles naturally secreted by stem cells, carrying a concentrated cargo of growth factors (VEGF, EGF, KGF, FGF), proteins, mRNA, and anti-inflammatory cytokines. Applied immediately after microneedling, exosomes penetrate the micro-channels and deliver this regenerative payload directly into the skin at the cellular level — far more powerfully than PRP alone. This protocol is recommended for patients seeking advanced skin rejuvenation, significant acne scar improvement, or skin recovery after laser or other procedures. NRS 10,000 per session.
6. Microneedling + PDRN — NRS 15,000
PDRN (Polydeoxyribonucleotide) is a highly purified DNA fragment derived from salmon DNA that activates the skin’s A2A adenosine receptors — stimulating tissue repair, collagen synthesis, angiogenesis (new blood vessel formation), and anti-inflammatory activity at the cellular level. When delivered via microneedling micro-channels, PDRN reaches the dermis directly, making it exceptionally effective for deep skin regeneration, wound healing, severe acne scars, and anti-aging. It is one of the most advanced regenerative ingredients used in aesthetic dermatology today. NRS 15,000 per session.
7. MNRF — Microneedling Radiofrequency
MNRF is the most advanced form of microneedling, combining insulated needles with radiofrequency energy delivered at the exact moment the needles reach their target depth in the dermis. This dual mechanism stimulates far deeper collagen remodeling than standard microneedling and is the gold standard treatment for acne scars, skin tightening, and open pores. NPR 15,000 per session (NPR 25,000 for a 3-session package).
Who Is It Best For?
- Dull, fatigued, or aging skin seeking overall rejuvenation
- Mild to moderate acne scars (ice pick, boxcar, rolling)
- Fine lines, early wrinkles, and early skin laxity
- Hyperpigmentation, melasma, dark spots, and post-acne discoloration
- Enlarged pores and rough skin texture
- Anyone wanting a non-ablative treatment with minimal downtime
- All skin types and tones — microneedling is safe for darker skin tones unlike many lasers
- Patients wanting to enhance the absorption of active serums and growth factors
- Those seeking advanced regenerative protocols (PDRN, exosome) for deep skin repair
Note: For deep or severe acne scars, MNRF or CO2 laser may be recommended over standard microneedling. Our doctors will advise the most appropriate treatment at consultation.
Microneedling vs MNRF vs CO2 Laser
Choosing the right collagen-stimulating treatment depends on your skin concern, skin tone, and tolerance for downtime:
Feature | Microneedling (Dermapen) | MNRF | CO2 Laser |
Technology | Mechanical micro-injury | Needles + RF energy | Ablative laser |
Collagen stimulation | Superficial–mid dermis | Deep dermis | Deep dermis |
Safe for dark skin | Yes | Yes | With caution |
Downtime | 1–3 days | 2–5 days | 5–10 days |
Acne scar improvement | Moderate | Excellent | Excellent |
Pain level | Minimal (with numbing) | Minimal (with numbing) | Moderate |
Sessions needed | 3–6 | 3–4 | 1–3 |
Our dermatologists will recommend the most appropriate protocol — or a combination — based on your individual skin assessment.
What Does Microneedling Treat?
- Acne scars — Ice pick, boxcar, and rolling scars respond well to microneedling, particularly when combined with PRP, exosome, PDRN, or upgraded to MNRF.
- Collagen induction — Stimulates the skin’s own structural proteins for firmer, more youthful skin.
- Skin rejuvenation — Overall improvement in glow, radiance, and skin health.
- Hyperpigmentation — Fades dark spots and uneven skin tone; tranexamic acid protocol delivers targeted depigmentation.
- Fine lines and wrinkles — Reduces the depth and visibility of expression lines and early aging.
- Open pores — Tightens the skin around pores through collagen remodeling, visibly reducing pore size.
- Melasma — Tranexamic acid + microneedling is particularly effective for melasma and stubborn pigmentation.
- Skin texture — Smooths rough, bumpy, or uneven skin surface.
- Stretch marks — Improves the texture and color of stretch marks on the abdomen, thighs, and arms.
- Deep skin regeneration — PDRN and exosome protocols accelerate tissue repair and are ideal for post-procedure recovery and advanced aging concerns.
- Enhanced product absorption — Micro-channels allow active serums to penetrate far deeper than topical application alone.
Results You Can Expect
After microneedling, the skin may appear mildly red for 1–3 days — similar to a mild sunburn. This is completely normal and part of the healing response. Within 1–2 weeks, the skin settles and begins to visibly improve in texture, tone, and glow.
Significant collagen remodeling develops over 4–8 weeks following each session, with optimal results visible after completing a full course of 3–6 sessions spaced 4 to 6 weeks apart. When combined with PRP, exosome, or PDRN, results are typically faster and more pronounced. Strict sun protection with SPF 30+ is advised for at least 2 weeks after each session.
What to Expect During Your Session
- Consultation — Our dermatologist assesses your skin concern, type, and medical history and recommends the most appropriate microneedling protocol.
- Blood draw (for PRP) — If PRP is selected, a small amount of blood is drawn and centrifuged for approximately 20 minutes to extract the platelet-rich plasma.
- Preparation — The face is cleansed. A topical numbing cream is applied for 20 to 30 minutes before the procedure for comfort.
- Microneedling — The dermapen device is passed over the treatment area at the appropriate depth setting for your concern. You will feel a mild vibrating pressure throughout.
- Active serum application — PRP, meso solution, tranexamic acid, exosome, or PDRN is applied immediately after needling to penetrate deeply through the micro-channels.
- Post-care — A soothing serum and SPF are applied. You receive detailed aftercare instructions.
Session duration: 45–75 minutes depending on protocol. Downtime: 1–3 days (standard microneedling) | 2–5 days (MNRF).
Pre- and Post-Procedure Care
Before Your Session
- Avoid sun exposure and tanning for at least 1 week before treatment
- Discontinue retinoids and exfoliating acids (AHA/BHA) 5–7 days before
- Do not treat areas with active acne breakouts, infections, or open wounds
- Arrive with clean, makeup-free skin
After Your Session
- Apply only gentle, doctor-recommended moisturizer and SPF for the first 3–5 days
- Avoid makeup for 24–48 hours post-treatment
- Do not pick, scratch, or exfoliate the healing skin
- Avoid strenuous exercise, saunas, and steam for 48 hours
- Use SPF 30+ sunscreen daily — strict sun protection is essential for optimal results
- Avoid retinoids and AHA/BHA acids for 1 week after the session
Microneedling Price in Nepal
Treatment | Price (NRS) |
Microneedling (Dermapen) alone — per session | NRS 4,000 |
Microneedling + PRP (Vampire Facial) — per session | NRS 5,000 |
Microneedling + Meso Solution — per session | NRS 6,000 |
Microneedling + Tranexamic Acid — per session | NRS 6,000 |
Microneedling + Exosome — per session | NRS 10,000 |
Microneedling + PDRN — per session | NRS 15,000 |
MNRF (Microneedling Radiofrequency) — 1 session | NRS 15,000 |
MNRF — 3 session package | NRS 25,000 |
Frequently Asked Questions — Micro Needle Therapy Nepal
Micro Needle Therapy (dermapen microneedling) is a treatment using a device with multiple fine needles to create tiny controlled punctures on the skin’s surface. This triggers the skin’s natural collagen production, improving texture, tone, acne scars, fine lines, and overall skin quality.
Standard microneedling uses mechanical micro-injury alone to stimulate collagen in the upper-to-mid dermis. MNRF (Microneedling Radiofrequency) adds RF energy delivered at the exact needle depth into the deep dermis, stimulating far more powerful and deeper collagen remodeling. MNRF is the gold standard for acne scars and skin tightening.
PDRN (Polydeoxyribonucleotide) is a purified DNA fragment derived from salmon DNA that stimulates tissue repair, collagen synthesis, and new blood vessel formation at the cellular level. When delivered via microneedling micro-channels, PDRN reaches the dermis directly, making it exceptionally effective for deep skin regeneration, severe acne scars, anti-aging, and wound healing. Priced at NRS 15,000 per session.
Exosomes are nano-sized vesicles from stem cells, carrying a far more concentrated and standardized cargo of growth factors and regenerative signals than PRP. When applied via microneedling, they penetrate deeply and stimulate cellular regeneration more powerfully. Exosome microneedling is recommended for advanced rejuvenation, significant acne scars, and post-procedure skin recovery. Priced at NRS 10,000 per session.
Tranexamic acid inhibits melanin synthesis and is highly effective for melasma, stubborn hyperpigmentation, post-acne dark marks, and uneven skin tone. Delivered via microneedling micro-channels, it penetrates far deeper than topical application, making this protocol significantly more effective for pigmentation concerns. Priced at NRS 6,000 per session.
Discomfort is minimal. A topical numbing cream is applied 20 to 30 minutes before the procedure. Most patients describe the sensation as a mild vibrating pressure rather than pain throughout the session.
For general skin rejuvenation and mild concerns, 3–4 sessions spaced 4 to 6 weeks apart typically deliver excellent results. For acne scars, 4–6 sessions are recommended. For deep or severe scarring, upgrading to MNRF (3–4 sessions) delivers the most significant improvement.
Microneedling alone starts at NRS 4,000. With PRP: from NRS 5,000. With meso solution or tranexamic acid: NRS 6,000. With exosome: NRS 10,000. With PDRN: NRS 15,000. MNRF: NPR 15,000 per session or NPR 25,000 for a 3-session package.
Take the first step toward better health by scheduling your appointment today. Whether you’re a new patient or returning, our quick and secure booking form makes it easy to find a time that works for you.
If you have general questions about our services, doctors, or clinic policies, feel free to reach out via email and Call us directly.
akarshanskin@gmail.com
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+977-9813994443
